Vaping CBD vs Nicotine

Vaping CBD vs Nicotine

Vaping CBD to Quit Nicotine?

This is a rather lengthy post please feel free to skip to the sections that most interest you.

History of Vaping CBD vs Nicotine

The Vaping Revolution

Vaping Plant Extracts: CBD vs Nicotine

The Physical Effects of Vaping CBD vs Nicotine

Nicotine Addiction and Vaping CBD

Methods of Vaping CBD to Reduce Nicotine Level

You’ve seen them.

People puffing on tiny devices making tiny wisps of vapor.

Or maybe they’re using a bigger device, with tanks and making billowy clouds.

Well, more than likely these folks are vaping nicotine.

But, just maybe, they are vaping something else: CBD.

Vaping CBD hemp extract is becoming very popular. But, how does it differ from vaping nicotine products? How is it the same? What are the respective danger or benefits. Can you mix the two?

Well, keep reading and find out.

But first, a little history of vaping.

History of Vaping Hemp vs Tobacco

First of all CBD comes from hemp and nicotine is derived from tobacco.

So generally, when we talk about vaping CBD vs nicotine, it’s the same as saying vaping a hemp extract vs a tobacco extract.

Hemp and tobacco have both been used for millennia, and both have been revered and vilified. These two plants might be the most controversial crops ever cultivated.

But they are now on very different paths as far as public opinion is concerned.

Hemp is rapidly gaining interest an approval while tobacco continues its downward slide.

So It’s no wonder that hemp has taken over former tobacco fields in Kentucky, Tennessee and North Carolina.

But don’t count tobacco out. It’s still valuable for the nicotine that goes in e-liquids. In fact the invention of e-cigarettes in 2004 opened a new chapter in the long history of this remarkable plant.

“Vaping” nicotine became a thing long before vaping CBD. But even before that cannabis aficionados were already beginning to inhale cannabis without lighting up.

Meanwhile, cannabis aficionados were already beginning to inhale cannabis without lighting up.

Vaping Cannabis

Actually, hemp is a variety of cannabis. So if you vape hemp or CBD you are technically vaping cannabis. Just so you know.

But years before disposable CBD vape pens, cartridges, pods and sub-ohm tanks mods, there rather cumbersome appliances being used for vaping cannabis that were the original vaporizers.

The Storz and Bickel Volcano and the Vapor Brothers Vape Box both came out around 1999 and were the first commercially successful vaping devices. They are still manufactured to this day.

Vape box on the ground
Not going to fit in your pocket By Cstills3632
Volcano Vaporizer
The Volcano – Vapin’ Old School By Coaster420

These contraptions force hot air – around 300 degrees – through ground-up weed and extract the good stuff without combustion.

Vape and vaping now entered the English language.

Pot smokers realized that vaping was better and more efficient than because the higher temperatures of lighting cannabis destroy many of its desirable compounds.

And it is reasonable to assume that vapor is much less toxic than smoke.

The advantages of vaping were becoming evident.

Furthermore,  just around the corner, a new technology would open up endless possibilities for vaping the extracts of cannabis, hemp, tobacco  – THC, CBD and nicotine. 

E-Cigarettes and the Vaping Revolution

E-cigarettes hit the scene in China in 2004. And that changed everything.

Let’s face it. It was a stroke of genius.

Smoking cigarettes is deadly. Nicotine is addictive. Let’s figure out a way to deliver nicotine that doesn’t involve setting stuff on fire.



Mix pure nicotine with a carrier liquid (coconut oil or citrus ester), give it a little electric charge and you get vaporized nicotine.

Add some menthol and you have an approximation of smoking a real cigarette. No lighter or ashtray needed.

Convenient, discreet and clean. Safer then inhaling smoke.

Oh, and one other big difference – the levels of nicotine can be increased easily. More on that later.

So now we have a device that is  a delivery method for plant extracts.

The era of modern vaping had arrived. 

Vaping Plant Extracts – CBD and Nicotine

It took some time for vaping technology to expand beyond the e-cigarette (disposable vape pen), but within 10 years, we had handheld herb vaporizers, cartridges, tank mods and pod systems.

Between the new vaping technologies and extraction methods, manufacturers have a virtually infinite amount of variations of products to order.

On top of that, with refillable pods, cartridges and tanks, the consumer can further customize what they are vaping.

vaping devices for CBD and nicotine

So whether you want to vape CBD, nicotine or a combination, the choices are endless – and a bit overwhelming.

But basically, any way you can vape nicotine you can vape CBD as well.

For further reading, here is a guide to the ways to vape CBD.

So now let’s look at the what the physical effects of vaping CBD and nicotine are, how they differ and how they might interact.

Physical Effects of CBD vs Nicotine

First off, The effects of nicotine are much better understood than CBD/hemp. That’s because until very recently studying cannabis was tightly restricted by federal US laws. That’s changing rapidly due to the 2018 Farm Bill.

But let’s look at what we know.


Nicotine is a compound produced by the tobacco (and other nightshade plants) to repel insects.

To humans It is a addictive stimulant drug.

Nicotine affects our nervous system because it is nearly identical to acetylcholine – an important messaging molecule.

Acetylcholine is a neurotransmitter – a vital messaging molecule that signals information to the brain about our blood pressure, heart rate, respiration and alertness.

We have acetylcholine receptors throughout our body, and when we inhale nicotine, it fits right into these receptors tricking our brain. Adrenaline rises. Our blood vessels constrict, our pulse, breathing, blood pressure and attention all increase.

We get that familiar rush or buzz. Plus, the brain releases, endorphins and dopamine, giving us a reinforcing, pleasurable feeling.

Is it any wonder that people get hooked?

Long Term Effects of Nicotine

Nicotine Addiction

older woman vaping CBD

As you know, nicotine is highly addictive. Long term use changes your body chemistry. Specifically, it alters acetylcholine receptors and acetylcholine production.

In other words, because nicotine has essentially replaced the acetylcholine in your body, your brain stops sending signals to make more. So when you don’t get any nicotine in your system, you feel really crappy.

Health Concerns

The jury is still out as far as long term effects of nicotine use. This is because the normal delivery method – smoking – is far more dangerous than the nicotine itself.

However, unless you have existing cardiovascular disease, there is not much evidence that nicotine is dangerous in and of itself.

In fact a study of smokeless tobacco users found no damage to the circulatory system or internal organs.

Most healthcare officials would have to (reluctantly) admit that vaping nicotine poses far less risk than smoking.

However, nicotine vaping – especially with the advent of powerful nic salts – can deliver far more nicotine per puff than cigarettes.

A little nicotine does not appear to be harmful, but people are consuming it in unprecedented amounts. We don’t know what the effects might be down the road.

If you want to cut back on nicotine, vaping CBD may be a good idea. Let’s take a look why.

Physical Effects of Vaping CBD

man vaping CBD by a river

When you vape CBD it enters your bloodstream almost immediately and goes to work. It doesn’t affect your nervous system directly like nicotine. It acts upon your endocannabinoid system.

This is a network or receptors throughout our body that we didn’t even know about 30 years ago.

The endocannabinoid system is best thought of as the moderator of all of the other systems of our body. Its job is to resolve imbalances. There are receptors throughout the brain and body connected to it.

When you vape CBD/hemp, you are feeding these receptors and giving the endocannabinoid system what it needs to do its job – right away.

So vaping CBD may not have the same set of effects vaping nicotine. But if you have pain, anxiety or depression, it can be dramatic.

Vaping CBD can bring on a calm feeling of relief and well being.

Unlike nicotine, CBD actually reduces adrenaline.

Furthermore, as a result of a rather complicated relationship with your different serotonin receptors, CBD has a positive effect on serotonin levels.

Long Term Effects of CBD
CBD Distillate Vape Cart

CBD is not addictive and generally considered safe for long term use.

However, at high doses there does seem to be a potential for building a tolerance to CBD over time. So proper dosing is important.

Differing Effects of Vaping CBD and Nicotine

So when you are considering the various effects of vaping CBD vs nicotine, here are some things to keep in mind.

  • Vaping nicotine raises adrenaline levels
  • CBD vaping can lower adrenaline
  • Vaping nicotine increases blood pressure, heart rate and respiration
  • CBD can bring on an overall calming effect
  • Vaping nicotine can improve short-term focus and attention
  • Nicotine prompts the release of endorphins and dopamine
  • CBD has been shown to have a positive effect on serotonin levels
  • Nicotine is highly addictive
  • Vaping CBD is not addictive – in fact may reduce addiction
  • Long-term health effects of nicotine are uncertain
  • CBD is considered safe long term

Nicotine Addiction and CBD

Nicotine is highly addictive. It’s comparable to heroin or cocaine.

However, vaping CBD just might be an effective way to reduce addiction to nicotine.

As we have stated, the main reason that nicotine is so addictive is that it reduces the body’s natural production of acetylcholine.

The user must continue to consume nicotine or experience unpleasant withdrawal symptoms.

On the other hand, CBD has been shown to increase levels of acetylcholine.

If this is true, the major chemical factor of nicotine addiction can be counteracted by consuming CBD.

This could be why in a recent study, CBD was reduced the urge to smoke by 40%.

Furthermore, CBD seems to lessen the power of cues that prompt people to smoke.

More research is needed but the results are very promising.

Vaping CBD to Reduce Nicotine

man vaping CBD

The invention of vaping technology allows for delivery of much higher concentrations of nicotine.

This is a problem – especially for teens.

But this same technology can deliver a decidedly more beneficial substance: CBD/hemp extract – which could help knock that nicotine monkey off your back.

Smoking cessation is a complicated and difficult subject, we are talking about people who are vaping high levels of nicotine.

Two Ways to Use CBD Vape to Help Decrease Nicotine

Here are two suggestions to try if you want to loosen the hold Old Nic has on you.

Keep in mind that it’s best to buy high quality, full spectrum CBD/hemp vape products – as long as THC is not an issue for you.

The CBD Switcheroo
JUUL type CBD pods

This method requires carrying around two devices – a bit inconvenient but worth it. 

Buy a vape pen and a highly concentrated CBD cartridge – at least 500 mg/ml. 

Alternate between your normal nicotine delivery device and this high-strength vape. You can either alternate puffs or switch mods between “sessions”.

You can start out one puff CBD for every three puffs of nic.  Over the course of a few days, work on increasing that ratio.  If you get up to 1:1, you’ve reduced your nicotine consumption by 50%.

If it works,  you can keep going until you quit.

Note: If you are using a pod system, just switch out your normal one with a CBD pod. Easy. 

The CBD Infusion Method
Avida CBD flavorless additive
Flavorless Additive

If you are using a sub ohm tank mod or refillable pod system, you can easily start cutting your regular e-liquid with CBD. 

You can buy flavored or unflavored CBD additive and mix it in. 

Start by adding about 25% and slowly increase it over time. 

You can also start buying lower nic concentrations at the same time. Keep going until you reach a lower level that you are comfortable with. 

Here are some points to keep in mind if you want to try vaping CBD to reduce nicotine levels:

  • Try alternating puffs between CBD and nicotine
  • Mix in CBD additive to your vape juice
  • Use highly concentrated CBD e-liquid
  • Buy full-spectrum CBD/hemp extract – if you can
  • Pod systems work best
  • Start low and slowly replace nicotine with CBD
  • Reduce nicotine strength simultaneously 
  • Set a goal and diligently work towards it 


Tobacco and hemp are at an intersection right now. 

Vaping CBD and vaping nicotine are both popular and have many things in common and many differences. 

The reasons for using them quite often overlap. 

Nicotine is not terribly bad in small amounts, but heavy consumption can take a toll. 

CBD on the other hand has many benefits. And vaping CBD/hemp can provide a lot of the effects on vaping nicotine without the addiction. 

So whether you reduce or replace nicotine with CBD, I hope this post has been helpful. 

Breath in the goodness of CBD

John Astrab


Neither Hemp nor its byproducts are medicine. They not intended to treat any specific ailment. We make no claims as such.

All information, content, and material of this blog post is for informational purposes only and not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.

Ultimately, all healthcare decisions are yours and yours alone.

Please follow and like us:


Leave a Reply

Your email address will not be published. Required fields are marked *


Enjoy this blog? Please spread the word :)

CBD Vape 4 Life